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International Journal of Pharmacology and Pharmaceutical Technology

Abstract

As we humans are far too aware, all mammals have a finite lifespan. Apart from basic longevity, age is also a major risk factor for most of the diseases. Since stem cells are responsible for maintaining tissue homeostasis throughout an organism’s lifetime, an attractive theory is that ageing-related phenotypes might be, at least in part, due to an alteration in the number and/or function of tissue stem cells. Here, we have focused on kupffer cell regeneration after ethanol cytotoxicity and possible role of cytokines and oxidative stress enzymes during the cascade along with genopreventive effect of Triphala in mouse bone marrow cell.

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